Table 1 Clinical findings in patients with methaemoglobinaemia Methaemoglobin concentration Clinical findings 13 None 315 Possibly none; pulse oximeter will read low oxygen saturations 1520 Cyanosis (central and peripheral); not improving with oxygen administration 2050 Dyspnoea, headache, fatigue, dizziness, syncope, weakness 5070 Tachypnoea, metabolic acidosis, dysrhythmias, seizures, central nervous system depression, coma 70 Grave hypoxic symptoms, death Open in a separate window Pulse oximetry is inaccurate in patients with methaemoglobinaemia, as the pulse oximeter reading is based on the assumption that the only two varieties of haemoglobin present are oxyhaemoglobin and deoxyhaemoglobin.Copyright 2011 The British Pharmacological Society This article has been cited by other articles in PMC.Abstract Methaemoglobinaemia cán cause significant tissué hypoxia, leading tó severe, potentially Iife-threatening clinical féatures andor death.
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